The human immune system is often overlooked yet without it we would not get very old at all. Our immune system is a complicated system, designed to both protect and defend us against microbes that could do us harm. Our immunity is based on many factors, most of which are tied into the presence of key nutrients needed for proper immune function. Nutrients for immunity are many and include beta D Glucan, mycelial mushroom extracts, colostrums, and others. Beta Glucan mycelial mushroom extract, and colostrums, when combined with key vitamins and minerals can provide significant immune enhancement. These immune supplements vary in their action, but if they are to be taken for some time, it is essential that the immune supplement provide both stimulation and nourishment for the immune system. Over-stimulation of the immune system over long periods of time can result in immune exhaustion. Natural immune support should be approached from a variety of ways and any targeted supplement for immune support should address all the known factors of natural immune enhancement. Beta D Glucan and mycelial mushroom extracts and colostrums can be costly, but when combined with other known nutrients for immunity, we can use less of these compounds and still achieve the maximum immune enhancement.